Slay the Spire Slay the Spire: How to Unlock Everything (All Characters, Relics, Cards)
Complete guide to unlocking all 4 characters, 300+ cards, 200+ relics, and Ascension levels in Slay the Spire. Includes achievement hunting tips and beta card unlock methods.
Complete guide to unlocking all 4 characters, 300+ cards, 200+ relics, and Ascension levels in Slay the Spire. Includes achievement hunting tips and beta card unlock methods.
Data Sources
This guide is based on Slay the Spire game data as of the version indicated above. Game mechanics and balance may change with updates. Verify details in-game for the most current information. Last reviewed: May 5, 2026.
Related Guides
Slay the Spire: Complete Beginner's Guide (2026)
Master the fundamentals of Slay the Spire with this comprehensive guide covering all 4 characters, map pathing, card evaluation, and essential strategies for your first successful climb.
Slay the Spire: All Characters Tier List & Best Builds (2026)
From the beginner-friendly Ironclad to the stance-dancing Watcher, we rank all 4 characters by overall power, difficulty, and build diversity. Includes best archetypes for each character.
The Binding of Isaac: How to Unlock All 34 Characters
Complete guide to unlocking every character in The Binding of Isaac: Rebirth and all DLCs. From Eve to The Forgotten, learn the exact requirements for each unlock.
Search for more